Hosting Application written in NodeJs or Python

Want to migrate to CyberPanel from cPanel.

Here comes the question - can I host other application rather than PHP websites?

I’ve got several projects written in Flask and NodeJs. Can I host that apps with CyberPanel without additional expenses and issues?

You need to use a reverse proxy. For example, you can setup flask application with gunicorn and use rewrite rules to proxy the traffic to gunicorn backend, for more information you can read Proxy Preserve Host — CyberPanel - WebHosting Control Panel for OpenLiteSpeed