Help with DNS seetting

Hello. Till now I used ISP Config where I didn´ t set dns at all. I just have my domain registrar and his nsset where I manage domains and subdomains and in ISP config I only created new website and all run without problem.

Is there some way how to turn off dns in CP?
Or I just must to create something?
My created website shows Error500 and I think this is because DNS on CP not properly set. Please any idea?
Thank you