Emails not delivering

Please help me I am unable to send mesages from my server. the details below is from mail log

Feb 18 14:37:17 hostinator postfix/error[1890027]: 15FBC30004BE:, relay=none, delay=271033, delays=268178/2852/0/2.5, dsn=4.0.0, status=deferred (delivery temporarily suspended: host[] refused to talk to me: (mxweb013) Nemesis ESMTP Service not available 421-Service unavailable 421-Reject due to policy violations. 421 For explanation visit WEB.DE Senderguidelines)

check the SMTP and credential info

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