I’ve been using Cyberpanel and Wordpress with php v 8.1 since around May without issues, most of the issues I encounter relates to plugins and incompatibility.
However: lsphp installed with Cyberpanel misses a lot of extensions and packages are not available.
I managed to get everything working by going manual and compiling.
You can follow my instruct here: Php 8.1 error in INSTALL PHP EXTENSIONS - Support and Discussion / General Discussion - CyberPanel Community